MDoloris Patient Monitor for Nociception ANI Monitor V2

The MDoloris Patient Monitor for Nociception ANI Monitor V2 is a Class IIa medical device designed to continuously measure the balance between nociception and antinociception by analysing heart rate variability and the sympatho-vagal balance. Used in general anaesthesia and conscious patient care, it provides an objective assessment of a patient’s comfort or discomfort, helping to adjust opioid titration. Validated by numerous scientific publications, it is a valuable tool for optimising pain management, reducing the adverse effects of overdoses and improving perioperative care.

The MDoloris Patient Monitor for Nociception ANI Monitor V2 is a Class IIa medical device designed for continuous monitoring of the balance between nociception and antinociception. By analysing heart rate variability and the sympatho-vagal balance, it provides practitioners with an objective measure of a patient’s comfort or discomfort. This accurate monitoring is applicable in general anaesthesia, where it helps maintain optimal analgesia, as well as in conscious patients, particularly those unable to communicate their pain effectively. Unlike a conventional multi-parameter monitor, it focuses on a specific physiological parameter, providing targeted and actionable information for pain management.

Assistance with Personalised Opioid Titration

In anaesthesia, an ANI between 50 and 70 indicates adequate analgesia. A drop below 50, especially if it falls below 40 or 30, predicts with a high probability the imminent onset of haemodynamic reactivity, giving the anaesthetist time to adjust the treatment. Conversely, a value above 70 may indicate opioid overdose, with an increased risk of side effects such as bradycardia, hypotension, respiratory depression, nausea or postoperative hyperalgesia. The device thus reduces unnecessary administration, optimising patient safety and comfort. It is particularly relevant for at-risk populations such as elderly, paediatric, obese, drug-dependent or non-communicative patients, and for long procedures requiring fine titration of analgesics.

Scientific Validation and Clinical Benefits

Validated by numerous international publications, the ANI Monitor V2 has established itself as a reliable tool for predicting post-operative pain, detecting haemodynamic reactions and diagnosing the failure of regional anaesthesia. Studies show that it outperforms heart rate and blood pressure in detecting nociception. Used in various surgical specialties, it helps reduce opioid doses by 30 to 60%, thereby limiting adverse effects and promoting faster recovery. Its ability to provide objective, real-time data makes it a valuable ally in personalising care, improving the quality of care and optimising patient comfort throughout the surgical journey.

Technical Details